Skip to main content
Fig. 4 | Respiratory Research

Fig. 4

From: A flavanone from Baccharis retusa (Asteraceae) prevents elastase-induced emphysema in mice by regulating NF-κB, oxidative stress and metalloproteinases

Fig. 4

Oxidative stress in lung tissue. 8-iso-PGF-2α-positive area (mean and SE) within the lung parenchyma a. Representative photomicrographs of the lung parenchyma immunostained for 8-iso-PGF-2α b-d. Vehicle-treated animals that received elastase showed an increase in the 8-iso-PGF-2α-positive area c compared with animals in the control group b. This response was attenuated in elastase-treated animals that received sakuranetin treatment d compared with the ELA+Ve animals c. Arrows represent the isoprostane-positive area. *p < 0.001 compared with the SAL+Ve group; **p < 0.001 compared with the ELA+Ve group

Back to article page