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Fig. 4 | Respiratory Research

Fig. 4

From: Fibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients

Fig. 4

Snail1 and E-cadherin protein expression in non-COPD and COPD lungs. Immunohistochemical localization of EMT markers in the airway epithelium of non-COPD (a, c, e) and COPD (b, d, f) lungs (n = 3). Immunostaining for E-cadherin (a, b) and Snail1 transcription factor (c, d) and N-cadherin (e, f). The dark brown color is indicative of strong expression (denoted by red arrows) of E-cadherin in non-COPD (a), Snail1 in COPD (d) and N-cadherin in COPD (f) lung. Negative control was stained with isotype-matched control antibody (data not shown). Non-COPD subjects are non smokers. aw: airway lumen

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