Skip to main content
Fig. 8 | Respiratory Research

Fig. 8

From: Protective effect of a Protein Epitope Mimetic CCR10 antagonist, POL7085, in a model of allergic eosinophilic airway inflammation

Fig. 8

Representative lung tissue sections (3 μm) showing peribronchial inflammatory infiltrates 24 h after the last saline or OVA challenge. a Staining with haematoxylin & eosin (magnification x100). b Immunolabelling of CCR10 in mice challenged with saline (vii) or OVA (viii). CCR10 is expressed on bronchial and arterial smooth muscle, epithelial and endothelial cells, and occasional inflammatory cells (magnification x400 or x630). c Immunolabelling of CCR10 on lung sections (magnification x200). Mice received the following treatments: (i) vehicle, saline challenge, (ii) POL7085 15 mg/kg, saline challenge, (iii) vehicle, OVA challenge, (iv) POL7085 7.5 mg/kg, OVA challenge, (v) POL7085 15 mg/kg, OVA challenge, (vi) DEX 1 mg/kg, OVA challenge

Back to article page