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Fig. 2 | Respiratory Research

Fig. 2

From: The LIM-domain only protein 4 contributes to lung epithelial cell proliferation but is not essential for tumor progression

Fig. 2

Loss of Lmo4 results in impaired lung repair following H1N1 infection. a Percentage of EpCAM+CD104+ cells in the lungs of naïve control or Shh-cre;Lmo4 fl/fl animals. Data represent mean ± S.E.M., n = 5 animals per group. b Representative immunofluorescence staining showing the expression of Lmo4, keratin 5 and p63 in wild-type lungs 11 days post infection with H1N1 PR8 (10PFU). Scale bars = 25 μm. c Kaplan-Meier curve showing the survival of Shh-cre;Lmo4 fl/fl animal (n = 27) compared to control animals (n = 69) following infection with PR8 flu virus. d Representative H&E and immunohistochemistry showing the expression of keratin 5, p63 and the proliferation marker Ki67 in control and Shh-cre;Lmo4 fl/fl mice 11 days post infection with H1N1 (10PFU). Scale bars = 50 μm

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Respiratory Research

ISSN: 1465-993X

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