Fig. 5From: Epigenetics of Notch1 regulation in pulmonary microvascular rarefaction following extrauterine growth restrictionAltered DNA methylation levels of distal CpG sites in Notch1 promoter in postnatal and adult rats. CpG methylation profile in the BS1, BS2 of 3-week-old (a-b) and 9-week-old rats (d-e). White bars represent control values, black bars represent EUGR. Representative methylation sample are shown (c, f); each horizontal row of beads represents 11 CpG sites. Open circles indicate unmethylated CpG sites, while solid circles indicate methylated CpG sites. *P < 0.05. Data are presented as mean ± SEM. (n = 3 rats per group)Back to article page