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Table 4 Associations between biomarker levels and clinical parameters

From: Accelerated extracellular matrix turnover during exacerbations of COPD

 

FEV1 %pred

FVC %pred

6MWD

C3M

−0.118

−0.201

−0.350** (−0.311*)

C4M

−0.149

−0.161

−0.289* (−0.252)

C6M

−0.096

−0.226

−0.403** (−0.354**)

ELM7

−0.090

−0.149

−0.178

EL-NE

−0.039

−0.106

−0.186

VCANM

−0.0004

−0.080

−0.067

Pro-C3

0.345* (0.320*)

0.313* (0.305*)

0.055

P4NP 7S

−0.086

−0.193

−0.269* (−0.230)

Pro-C6

0.023

−0.046

−0.153

  1. Results are presented as univariate correlation coefficients (r) for each marker. In brackets are given multivariate correlation coefficients for markers showing significant r. The multivariate linear regression analysis included age, gender, BMI, smoking pack years, and smoking status as additional explanatory variables. Significance levels: *P <0.05, **P <0.01. FEV1, forced expiratory volume in one second; %pred, percentage of predicted value; FVC, forced vital capacity; 6MWD, 6 min walking distance