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Figure 9 | Respiratory Research

Figure 9

From: Decreased expression of the NF-κB family member RelB in lung fibroblasts from Smokers with and without COPD potentiates cigarette smoke-induced COX-2 expression

Figure 9

Systemic expression of Cox-2, RelB and miR-146a levels in COPD. Peripheral blood was obtained from subjects recruited as part of the CanCOLD project and total RNA, including miRNA, was isolated and the expression of Cox-2 and RelB mRNA as well as miR-146a evaluated by qRT-PCR. A total of 16 subjects from each category were analyzed from the CanCOLD cohort; each symbol represents a different individual. (A) RelB mRNA- there was no significant difference in the relative expression of RelB mRNA between the subject categories. (B) Cox-2 mRNA: there was no significant difference in the relative expression of RelB mRNA between the subject categories. (C) miR-146a: there was a significant increase in relative miR-146a expression in COPD Gold 1 compared to Normal subjects.

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Respiratory Research

ISSN: 1465-993X

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