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Figure 7 | Respiratory Research

Figure 7

From: Decreased expression of the NF-κB family member RelB in lung fibroblasts from Smokers with and without COPD potentiates cigarette smoke-induced COX-2 expression

Figure 7

Basal miR-146a expression in human lung fibroblasts from Normal subjects as well as smokers with and without COPD. (A) miR-146a-lung tissue: There was a significant increase in miR-146a in lung tissue derived from COPD subjects compared to Normal. Results are expressed as mean ± SEM and each symbol represents a different individual (Normal, n = 10; At Risk, n = 9; COPD = 9). (B) miR-146a-fibroblasts: There was no significant difference in basal miR-146a expression in lung fibroblasts derived from the three patient groups. Results are expressed as the mean ± SEM of miR-146a levels normalized to the snRNA U6 and are expressed as fold-change compared to Normal fibroblasts. Each symbol represents fibroblasts from a different individual (Normal, n = 5; At Risk, n = 13; COPD = 11).

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Respiratory Research

ISSN: 1465-993X

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