From: A randomized controlled trial of vitamin E and selenium on rate of decline in lung function
Full sample | Stratified by smoking status | |||||
---|---|---|---|---|---|---|
All treatment groups: | Unadjusted | Adjusted (model-based) | P value a | Never smokers | Former smokers | Current smokers |
Mean (SD) † | Mean (95% CI) †† | Mean (95% CI) †† | Mean (95% CI) †† | Mean (95% CI) †† | ||
Placebo | −63 (191) | −61 (−78, −43) | reference | −44 (−73, −15) | −58 (−82, −32) | −106 (−148, −63) |
Vitamin E | −45 (201) | −46 (−66, −29) | 0.2739 | −47 (−76, −18) | −42 (−67, −17) | −59 (−95, −21) |
Selenium | −67 (200) | −64 (−81, −47) | 0.6620 | −67 (−95, −38) | −75 (−100, −49) | −45 (−85, −5)* |
Vitamin E and Selenium | −45 (190) | −47 (−64, −29) | 0.2719 | −71 (−102, −40) | −30 (−55, −5) | −50 (−90, −10)* |
Marginal Models b : | ||||||
Any Selenium versus Placebo | Placebo | −61 (−78, −43) | reference | −44 (−73, −15) | −57 (−82, −32) | −106 (−148, −63) |
Any Selenium | −56 (−69, −44) | 0.7020 | −68 (−90, −47) | −52 (−70, −34) | −47 (−76, −19)* | |
Any Vitamin E versus Placebo | Placebo | −61 (−78, −43) | reference | −44 (−73, −15) | −57 (−82, −32) | −105 (−147, −63) |
Any Vitamin E | −46 (−58, −34) | 0.2058 | −59 (−80, −38) | −36 (−54, −18) | −54 (−81, −27)* |