Table 1 Patient characteristics at the time of diagnosis

Age (years)

47 ± 17

69 ± 10

<0.001

Female (%)

74

64

0.101

Body mass index (kg/m²)

26 ± 5

30 ± 6

<0.001

Diabetes (%)

19

57

<0.001

NYHA II/III/IV (n)

38/60/1

8/77/1

n/a

6 min walking distance (m)

386 ± 136

276 ± 117

<0.001

Right atrial pressure (mmHg)

7 ± 5

13 ± 5

<0.001

PAPm (mmHg)

53 ± 12

47 ± 10

<0.001

PAWP (mmHg)

8 ± 3

21 ± 5

<0.001

Transpulmonary gradient (mmHg)

46 ± 13

25 ± 10

<0.001

Diastolic gradient (mmHg)

24 ± 11

10 ± 8

<0.001

CO (L/min)

3.9 ± 1.2

4.9 ± 1.3

<0.001

CI (L/min/m²)

2.1 ± 0.6

2.5 ± 0.7

<0.001

PVR (dyn · s · cm⁻⁵)

1,017 ± 416

471 ± 218

<0.001

SvO₂ (%)

64 ± 9

63 ± 8

0.368

P_caO₂ (kPa)

9.5 ± 1.5

8.7 ± 1.2

0.039

P_caO₂ (mmHg)

71 ± 11

65 ± 9

P_caCO₂ (kPa)

4.4 ± 0.5

5.3 ± 0.7

<0.001

P_caCO₂ (mmHg)

33 ± 4

40 ± 5