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Table 1 Patient characteristics at the time of diagnosis

From: Capillary pCO2 helps distinguishing idiopathic pulmonary arterial hypertension from pulmonary hypertension due to heart failure with preserved ejection fraction

  IPAH (n = 99) PH-HFpEF (n = 86) p-value
Age (years) 47 ± 17 69 ± 10 <0.001
Female (%) 74 64 0.101
Body mass index (kg/m2) 26 ± 5 30 ± 6 <0.001
Diabetes (%) 19 57 <0.001
NYHA II/III/IV (n) 38/60/1 8/77/1 n/a
6 min walking distance (m) 386 ± 136 276 ± 117 <0.001
Right atrial pressure (mmHg) 7 ± 5 13 ± 5 <0.001
PAPm (mmHg) 53 ± 12 47 ± 10 <0.001
PAWP (mmHg) 8 ± 3 21 ± 5 <0.001
Transpulmonary gradient (mmHg) 46 ± 13 25 ± 10 <0.001
Diastolic gradient (mmHg) 24 ± 11 10 ± 8 <0.001
CO (L/min) 3.9 ± 1.2 4.9 ± 1.3 <0.001
CI (L/min/m2) 2.1 ± 0.6 2.5 ± 0.7 <0.001
PVR (dyn · s · cm−5) 1,017 ± 416 471 ± 218 <0.001
SvO2 (%) 64 ± 9 63 ± 8 0.368
PcaO2 (kPa) 9.5 ± 1.5 8.7 ± 1.2 0.039
PcaO2 (mmHg) 71 ± 11 65 ± 9
PcaCO2 (kPa) 4.4 ± 0.5 5.3 ± 0.7 <0.001
PcaCO2 (mmHg) 33 ± 4 40 ± 5