Microarray analysis identifies IL-1 receptor type 2 as a novel candidate biomarker in patients with acute respiratory distress syndrome

Table 4 Top up- and down-regulated genes in buffy coats from ARDS patients as compared to controls

Gene	Fold increase (ARDS vs. Control)	Gene	Fold decrease (ARDS vs. Control)
CEACAM6	24.78	CD28	−11.9
Defensin α-4	23.78	HDAC9	−8.64
Defensin α-1	23.52	CRTAM	−8.06
CEACAM1	22.81	SERPINB9	−7.96
FCER1G	18.52	MSRA1	−6.85
CD14	18.45	TGFBR3	−6.55
ITGB2	14.86	GPR183	−6.45
THBS1	14.77	KLRC1/2	−6.19
BPI	14.18	CD96	−6.17
IFITM3	14.08	PTPRC	−4.94
ARRB2	13.92	FAS Ligand	−4.73
ITGB2	13.74	PRKRA	−4.28
NCF4	13.61	ETS1	−4.06
VNN1	12.14	GZMA	−3.91
FCGR1 Family	12.08	IL-15	−3.56
LILRA2	11.21
PGLYRP1	11.09
CAMP	10.45
CEACAM8	10.34

ISSN: 1465-993X