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Table 1 Histopathological alterations of mice lungs exposed to HDM

From: Treatment with a sphingosine analog after the inception of house dust mite-induced airway inflammation alleviates key features of experimental asthma

 

Saline

 

HDM

 

Treatments

VEH

AAL-R

VEH

AAL-R

Perivascular infiltration of mononuclear cells

0

0

2*

1

Peribronchial/bronchiolar infiltration of mononuclear cells

0

0

2*

1

Perivascular infiltration of granulocytes

0

0

2*

1

Hypertrophy/hyperplasia of the bronchial epithelium

0

0

3*

1

  1. Results are expressed as median scores for each group, graded on a scale from 0 (no alteration) to 5 (severe alterations).
  2. 4–5 mice per group were analyzed. * P < 0.001 between HDM and Saline; P < 0.01 between AAL-R and vehicle.