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Figure 6 | Respiratory Research

Figure 6

From: Treatment with a sphingosine analog after the inception of house dust mite-induced airway inflammation alleviates key features of experimental asthma

Figure 6

Effects of non- or pre-phosphorylated analogs in draining lymph nodes. Single-cell suspensions derived from MLNs were obtained to determine: A) the total number of AFneg SSClow CD90.2+ CD8neg CD4+ T cells; B) the total number of AFneg SSClow CD90.2neg CD19+ B cells; C) the total number of MHC-IIhi CD11chi DC; D) the frequency of Ki67+ CD4+ T cells; E) the frequency of apoptotic/necrotic CD4+ T cells; and F) the frequency of apoptotic/necrotic CD19+ B cells. Apoptosis and proliferation could not be evaluated in saline mice given the paucity of cells. n = 6–8 mice per group and *signifies significant differences P <0.05. For panels A to C, means of all experimental groups are statistically different from SAL. Shown is representative of two independent experiments.

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Respiratory Research

ISSN: 1465-993X

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