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Figure 3 | Respiratory Research

Figure 3

From: MMP-12-mediated by SARM-TRIF signaling pathway contributes to IFN-γ-independent airway inflammation and AHR post RSV infection in nude mice

Figure 3

RSV infection results in enhanced AHR. Airway hyperresponsiveness to increasing doses of methacholine was assessed using plethysmography at days 1 (A), 3 (B), 5 (C), 7 (D) and 9 (E) post-RSV infection. Penh values were significantly increased at all indicated time points following RSV challenge in both BALB/c mice and nude mice. Graphs are represented as the mean ± s.e.m. Data were representative of two independent experiments performed on 10 animals per group. *, p < 0.05, **, p < 0.01, ***, p < 0.001 for RSV-infected versus mock-treated BALB/c mice; ^, p < 0.05, ^^, p < 0.01, ^^^, p < 0.001 for RSV-infected versus mock-treated nude mice.

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Respiratory Research

ISSN: 1465-993X

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