Table 3 Dendritic cell concentrations and characteristics

mDC (% of leukocytes)

0.19 [0.09-0.39]

0.14 [0.05-0.27]

0.15 [0.04-0.30]

<0.05

<0.05

0.354

mDC (10³/ml blood)

12.4 [5.0-26.5]

11.0 [3.5-29.2]

10.9 [3.6-31.2]

0.392

0.654

0.575

pDC (% of leukocytes)

0.09 [0.04-0.25]

0.08 [0.02-0.19]

0.09 [0.02-0.22]

0.595

0.740

0.749

pDC (10³/ml blood)

5.5 [2.8-15.4]

7.0 [1.7-19.4]

6.4 [1.5-16.9]

0.227

0.145

0.680

ratio mDC/pDC

1.9 [1.0-4.8]

1.3 [0.7-3.6]

1.7 [0.5-5.2]

0.084

0.141

0.575

mDC surface markers

BDCA-1 (% positive mDC)

61 [37–87]

67 [36–92]

72 [34–94]

0.505

<0.05

0.101

BDCA-3 (% positive mDC)

41 [14–77]

68 [24–100]

61 [20–99]

<0.001

<0.001

0.516

CD54 (MFI)

260 [177–373]

251 [87–355]

262 [160–445]

0.651

0.354

0.097

CD86 (% positive mDC)

24 [1–70]

56 [6–77]

44 [1–92]

<0.05

<0.05

0.953

PD-L1 (% positive mDC)

8 [0–31]

11 [1–66]

9 [0–41]

0.529

0.925

0.286

CCR5 (% positive mDC)

9 [0–63]

12 [0–75]

28 [0–91]

0.191

<0.01

0.200

OX40L (% positive mDC)

9 [1–91]

12 [0–32]

16 [5–72]

0.642

<0.05

<0.01

pDC surface markers

CD54 (MFI)

316 [181–480]

351 [251–715]

287 [0–698]

0.406

0.124

<0.05

PD-L1 (% positive pDC)

35 [4–62]

36 [9–73]

23 [0–80]

0.678

< 0.05

< 0.01