Figure 4
From: Inhibition of HMGCoA reductase by simvastatin protects mice from injurious mechanical ventilation
Proinflammatory cytokines in systemic circulation of ventilated mice. Levels of TNF-α (A) and IL-6 (B) were evaluated via ELISA in plasma of mice subjected to low tidal volume (LVt) or high tidal volume (HVt) mechanical ventilation for four hours. (NS: normal saline; Simva: Simvastatin; *denotes p < 0.05; **p < 0.01 and ***p < 0.001).