Figure 3
From: Inhibition of HMGCoA reductase by simvastatin protects mice from injurious mechanical ventilation
Effects of simvastatin treatment on airspace inflammation. (A) Total cell counts in broncho-alveolar lavage fluid (BALF) after 4 hours of mechanical ventilation. (B) Neutrophil fraction expressed as percent of total cells in BALF. (C) Quantification of matrix metalloproteinases −9 by ELISA in BALF samples of ventilated mice. (LVt: low tidal volume; HVt: high tidal volume; NS: normal saline; Simva: Simvastatin; *denotes p < 0.05; **p < 0.01 and ***p < 0.001).