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Figure 3 | Respiratory Research

Figure 3

From: Conditional overexpression of TGFβ1 promotes pulmonary inflammation, apoptosis and mortality via TGFβR2 in the developing mouse lung

Figure 3

Effect of TGFβ1 on lung apoptotic cell death. (A) TdT-mediated dUTP nick end labeling (TUNEL) was assessed in NB TGFβ1TG and TGFβ1TG X TGFβR2KO littermates where maternal dox exposure from PN7 – PN10 was carried out. Scale bar: 50 μm (B) Bar graph showing the percentage of TUNEL positive cells indicating the apoptosis quantification in TGFβ1TG mice and TGFβ1TG X TGFβR2KO littermates. (C) Representative serial sectioning images of cleaved caspase 3 and surfactant protein C staining in the lung specimens of TGFβ1TG mice and TGFβ1TG X TGFβR2KO littermates. Scale bar: 50 μm.

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