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Figure 6 | Respiratory Research

Figure 6

From: Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas

Figure 6

Comparison of large airway basal cell marker expression by FACS and mRNA analysis. (A) Scatter plot comparing the frequency of cell surface marker expression with corresponding marker mRNA expression in bulk population basal cells. The average percentage of marker expression was taken from Additional file 6: Table S2 and mRNA data were from Hackett NR et al., PLoS One, 2011. The mRNA expression data represent the average of five replicate microarray hybridizations, with the value for the most highly expressed probe for a given gene being plotted. The red line shows the linear relationship between the two properties (Pearson correlation r = 0.67; t = 7.85; p-value < 0.001). (B) Table of marker genes that were determined to be more than 5-fold enriched at the mRNA level in basal cells relative to other large airway epithelial cells. mRNA data are from Hackett NR et al., PLoS One, 2011, and are from the most highly expressed probe for the gene.

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