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Table 3 Characteristics of asthma remission and persistent asthma at age 18 years

From: Pathophysiological characterization of asthma transitions across adolescence

 

Asthma remission

Persistent asthma

p-value

FEV1 (L) Mean (SD)

4.2 (0.7)

3.9 (0.8)

0.04

N =

30

96

BHR (DRS) Mean (SD)

1.1 (0.2)

1.4 (0.5)

<0.001

N =

33

67

FeNO (ppb) Mean (SD)

27.2 (28.8)

56.3 (54.5)

0.002

N =

25

60

Atopy % (n)

40.6 (13)

76.6 (72)

<0.001

N =

32

94

Sputum data

N = 16

N = 22

 

Total cell count Median

31.5

38.0

0.41

(25–75 centiles)

(12.9-40.4)

(11.8-66.0)

% Epithelial cells Median

5.4

7.6

0.28

(25–75 centiles)

(1.4-11.1)

(3.3-13.8)

% Neutrophils Median

20.0

11.5

0.09

(25–75 centiles)

(8.3-40.8)

(5.5-24.3)

% Eosinophils Median

0.3

1.0

0.48

(25–75 centiles)

(0–1.4)

(0-3.9)

ECP (ng/ml)

35.5

119.5

0.09

(25–75 centiles)

(18.7-229.6)

(65.4-279.6)

  1. Notes:
  2. FEV1 was adjusted for height and sex.
  3. Means were compared using two sample T test. Pearsons chi-square test was used to compare differences in proportion. Non-parametric test (Mann–Whitney U test) was used to compare medians in the samples with non-normal distribution. Two sided significance was set at p <0.05.