Figure 1

The effects of quercetin on LPS-induced ALI. Mice were challenged with LPS or PBS 6 hours after intratracheal administration of quercetin or vehicle. After 24 hours, the lung tissue and BALF were collected. (A) The wet lung-to-body weight ratio. (B) Histological images of lung tissues. (b1) vehicle-PBS; (b2) quercetin-PBS; (b3) vehicle-LPS; (b4) quercetin-LPS. Original magnification: ×100. Each photograph represents three independent experiments. (C) Inflammatory cell numbers in BALF. Total, total cell count; Neut, neutrophils; Mono/Macro, monocytes/macrophages; Lym, lymphocytes. Vertically striped bars, vehicle-PBS; horizontally striped bars, quercetin-PBS, open bars; vehicle-LPS, filled bars; quercetin-LPS. Results are shown as the mean ± SD (*p < 0.05) of three independent experiments.