Figure 1

Protein expression of IL-17A/F in human lung explants exposed to cigarette smoke extract. Human lung explants from Non-COPD (A) and COPD subjects (B) were cultured with different concentration of cigarette smoke extract for 3 h or 6 h. The expression of IL-17A/F was detected by western blot. The results are presented as means ± SEM. The combination of cytokines (labeled as C) was used as a control. N = 10 for Non-COPD subjects and N = 8 for COPD subjects. CSE: Cigarette smoke extract. Cytokines: 20 ng/ml each of IL-1β, IL-6 and IL-23. ^*P < 0.05 compared with medium control. The label “M”, “2.5”, “5” and “10” represent medium, 2.5%, 5% and 10% of CSE respectively.