Table 1 Subject demographics and patient characteristics
Decrease (N?=?63) | No change (N?=?50) | Increase (N?=?41) | p value | |
|---|---|---|---|---|
Age (years) | 61.3 ± 14.6* | 59.5 ± 13.7** | 67.8 ± 11.2 | 0.011† |
Gender (M/F) | 27/36 | 21/29 | 14/27 | NS |
BMI | 23.7 ± 0.4 | 23.2 ± 0.5 | 22.1 ± 0.5 | NS |
Adult onset, n (%) | 45 (71.4) | 39 (78.0) | 34 (82.9) | NS |
Smoking status, never/ex/current (%) | 46/12/5 (73.0/19.1/7.9) | 38/8/4/ (76.0/16.0/8.0) | 26/11/4/ (63.4/26.8/9.8) | NS |
Atopic type, n (%) | 42 (66.6) | 30 (60.0) | 21 (51.2) | NS |
Pet owner, n (%) | 16 (25.4) | 11(22.0) | 9 (21.9) | NS |
Allergic rhinitis, n (%) | 30 (47.6) | 23 (46.0) | 15 (36.5) | NS |
Pollinosis, n (%) | 27 (42.8) | 24 (48.0) | 21 (51.2) | NS |
Treatment with higher than Step 4, (%)¶ | 17 (26.9) | 14 (28.0) | 20 (48.78) | 0.045‡ |
OCS on demand, none/rare/frequent (%) ? | 35/22/6 (55.6/34.9/9.5) | 40/8/2 (80.0/16.0/4.0) | 23/12/6 (56.1/29.3/14.6) | 0.046‡ |
Episode of acute exacerbation within a year | 15 (23.8) | 7 (14.0) | 15 (36.6) | 0.042‡ |
Eosinophils, % of WBC | 5.45 ± 0.48 | 4.75 ± 0.54 | 5.49 ± 0.60 | NS |
Pre-IgE, IU/L | 1020.6 ± 1654.8 | 873.5 ± 2018.3 | 695.8 ± 2555.9 | - |
Pre-IgE (log-transforn), IU/L | 2.59 ± 0.08*** | 2.40 ± 0.09 | 2.22 ± 0.10 | 0.014† |
FeNO, ppb | 52.2 ± 5.6 | 50.7 ± 6.3 | 50.5 ± 7.0 | NS |