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Figure 3 | Respiratory Research

Figure 3

From: Food allergy enhances allergic asthma in mice

Figure 3

Influence of exacerbation on lung and BAL inflammation in Der f-induced asthma model. (A) Eosinophil, neutrophil and lymphocyte counts in BAL and lungs one day after the first (day 28) and second challenge (day 35) in control (white bars) and asthmatic (black bars) mice. (B) Measurement of airway hyperresponsiveness (AHR) and airway resistances to increasing doses of methacholin in CTRL (white circles), sensitized (black circles), challenged (white diamonds) and asthmatic mice on day 28. (C) Total cells, lymphocytes, eosinophil and neutrophil counts in lungs one day after the first challenge (day 28) in CTRL (white bars), percutaneously sensitized (p.c, light grey), intra-nasally challenged (i.n, dark grey) and asthmatic (Der f, black) mice. (D) Measurement of IL-5, IL-10, IFN-γ and IL-17 secretion in BAL cells on day 28 and 35 in CTRL and Der f mice by ELISA. Data are represented as mean ± SEM (n = at least 5 mice/group). *p < 0.05, **p < 0.01, ***p < 0.001.

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