Table 4 Median (IQR) values of inflammatory markers in induced and spontaneous sputum samples by smoking, GOLD stage and H. influenzae carrier state

IL-6(pg/ml)

induced

17.2(5.7-36.2)

16.7(4.0-43.2)

0.63

16.7(4.5-67.8)

19.4(5.2-36.2)

0.78

20.7(10.9-49.0)

17.8(1.3-28.6)

0.16

spontaneous

10.2(3.0-29.5)

21.5(5.8-48.2)

0.22

15.6(2.2-64.9)

13.8(4.45.8)

0.79

32.2(22.4-75.38)

12.0(2.6-18.8)

0.01

IL-8(pg/ml)

induced

505.4(161.3-805.9)

517.0(193.3-1257.2)

0.54

233.4(170.0-1257.2)

529.0(224.5-1156.0)

0.37

277.6(170.0-649.0)

655.49(274.70-832.70)

0.32

spontaneous

221.0(165.4-674.4)

405.0(173.2-891.8)

0.42

210.1(112.7-844.1)

546.3(174.7-891.8)

0.18

336.9(210.1-734.2)

570.4(265.8-1141.4)

0.23

IP-10(pg/ml)

induced

216.5(130.9-826.2)

624.3(289.9-1844.9)

0.08

232.5(175.2-748.3)

600.8(216.7-1844.9)

0.20

477.5(175.2-2554.8)

696.1(56.0-1574.1)

0.85

spontaneous

345.6(124.9-716.5)

461.0(237.5-1361.7)

0.14

354.5(129.7-780.1)

448(237.5-1202.0)

0.33

491.9(285.2-2269.7)

582.7(180.0-1093.0)

0.42

TNF-α(pg/ml)

induced

0.4(0-1.9)

1.5(0-4.8)

0.34

0.00(0.00-2.5)

1.6(0-4.2)

0.14

2.3(0.0-5.1)

3.2(0.7-24.3)

0.24

spontaneous

0.9(0-3.2)

3.3(0.3-7.4)

0.20

0.5(0.0-4.5)

2.4(0.8-7.4)

0.18

6.43.7-14.0

7.9(2.1-173.9)

0.69

IL-18(pg/ml)

induced

9.0(0.9-19.3)

8.4(4.1-25.6)

0.58

10.6(2.4-14.9)

6.3(4.1-25.6)

0.91

5.04(0.0-13.6)

4.2(0.6-10.1)

1.0

spontaneous

2.9(0.5-14.8)

14.8(8.3-31.7)

0.01

8.8(1.0-15.1)

14.6(3.5-29.8)

0.24

10.4(5.0-13.9)

7.0(2.7-25.2)

0.45

MIG(pg/ml)

induced

332.2(30.1-661.7)

806.3(110.5-1391.4)

0.15

121.8(41.2-897.0)

661.7(110.5-1314.3)

0.27

157.8(43.3-1714.8)

677.1(179.0-961.8)

0.54

spontaneous

208.5(31.7-385.8)

626.8(222.6-2031.7)

0.03

280.4(69.8-1537.1)

383.4(205.3-1941.6)

0.47

1473.0 (438.8-4392.9)

740.5(384.6-2088.3)

0.33