Table 3 GWAS findings for FEV 1 /FVC in the LLFS (p <1E-07) and replication in the CHARGE/SpiroMeta consortia
From: Genetic variants associated with lung function: the long life family study
LLFS | CHARGE/SPIROMETA CONSORTIA | META ANALYSIS | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SNP | Chromosomal position | Gene | Coded/non-coded allele | Coded allele frequency | β (SE) | P_value | Coded allele frequency | β (SE) | P_value | Coded allele frequency | β (SE) | P_value | HetPVal | N |
rs889574* | Chr16: 89386808 | ANKRD11 | T/C | 0.31 | 0.129(0.025) | 1.63E-07 | 0.34 | 0.003(0.007) | 0.67 | 0.66 | −0.013(0.007) | 0.06 | 9.99E-07 | 50425 |