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Table 3 Clinical characteristics of COPD patients complicated with ABPA

From: The prevalence of increased serum IgE and Aspergillus sensitization in patients with COPD and their association with symptoms and lung function

 

Case 1

Case 2

Case 3

Case 4

Case 5

Case 6

Case 7

Case 8

Gender

Male

Female

Male

Male

Female

Female

Male

Male

Age (yr)

78

73

81

57

73

80

54

67

Chronic cough/sputum history (yr)

30

30

25

8

30

20

3

27

Dyspnea history (yr)

10

20

15

5

15

15

3

20

Ratio of dyspnea history to chronic cough/sputum history

0.33

0.67

0.60

0.63

0.50

0.75

1.00

0.74

Occurrence of wheezing

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Eosinophil of peripheral blood (%)

11.7

8.6

7.5

8.0

5.1

5.0

16.3

5.5

Serum T-IgE (kU/L)

7420

1239

5000

2049

1187

2272

1279

1160

Serum aspergillus specific IgE (kUA/L)

4.89

62.3

6.91

2.07

3.58

2.30

22

0.70

Serum aspergillus specific IgG (mg/L)

121

ND

102

ND

ND

92

ND

68

SPT (grade)

(++)

(+++)

(++)

(++)

(++++)

(++)

(++)

(++)

Chest HRCT

        

Central bronchiectasis

Yes

No

Yes

No

Yes

Yes

Yes

No

Mucoid impaction

No

No

Yes

No

No

No

No

No

Pulmonary opacities

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Lung function (postbronchodilator)

        

FEV1/FVC(%)

31

30

30

23

35

67

42

42

FEV1%predicted

35

26

25

14

39

36

30

23

Type of ABPA

CB

S

CB

S

CB

CB

CB

S

  1. Definition of abbreviations: ND: Not detected, SPT: Skin prick test, HRCT: high resolution computed tomography, T-IgE: Total IgE, FEV1: Forced expiratory volume in 1 second, FVC: Forced vital capacity, CB: Central bronchiectasis, S: Seropositive.