| |
Mpex†
|
AZ 1†
|
AZ 2†
|
|---|
|
SGRQ total‡(N = 233)
|
6MWT distance‡(N = 231)
|
SGRQ-C total‡(N = 745)
|
6MWT distance‡(N = 745)
|
FPI-SF total‡(N = 155)
|
SGRQ-C total‡(N = 586)
|
ISWT distance‡(N = 596)
|
|---|
|
E-RS Scores
| | | | | | | |
|
RS-Total Score
|
0.65**
|
-0.30***
|
0.52**
|
-0.14***
|
-0.43***
|
0.51**
|
-0.18***
|
|
RS-Breathlessness
|
0.60**
|
-0.33***
|
0.54**
|
-0.15***
|
-0.47***
|
0.52**
|
-0.19***
|
|
RS-Cough and Sputum
|
0.45**
|
-0.14*
|
0.42**
|
-0.10**
|
-0.28***
|
0.41**
|
-0.12**
|
|
RS-Chest Symptoms
|
0.50**
|
-0.17**
|
0.40**
|
-0.10**
|
-0.28***
|
0.44**
|
-0.15***
|
- †Spearman's rank-order correlation; E-RS mean weekly scores (Day -7 to Day -1).
- ‡Clinic visit, Day 1, prior to treatment.
- Bold coefficients identify constructs with strongest expected relationship.
- *p < 0.05; **p < 0.01; ***p < 0.001.
- Abbreviations: 6MWT 6-minute walk test, AZ AstraZeneca, E-RS Exacerbations of Chronic Pulmonary Disease Tool - Respiratory Symptoms, FPI-SF Functional Performance Inventory - Short Form, ISWT Incremental Shuttle Walk Test, SGRQ St. George's Respiratory Questionnaire, SGRQ-C St. George's Respiratory Questionnaire for COPD.
