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Table 4 Correlations † between E-RS scores and indicators of health status, exercise capacity, and functional performance

From: Measuring respiratory symptoms of COPD: performance of the EXACT- Respiratory Symptoms Tool (E-RS) in three clinical trials

 

Mpex†

AZ 1†

AZ 2†

SGRQ total‡(N = 233)

6MWT distance‡(N = 231)

SGRQ-C total‡(N = 745)

6MWT distance‡(N = 745)

FPI-SF total‡(N = 155)

SGRQ-C total‡(N = 586)

ISWT distance‡(N = 596)

E-RS Scores

       

 RS-Total Score

0.65**

-0.30***

0.52**

-0.14***

-0.43***

0.51**

-0.18***

 RS-Breathlessness

0.60**

-0.33***

0.54**

-0.15***

-0.47***

0.52**

-0.19***

 RS-Cough and Sputum

0.45**

-0.14*

0.42**

-0.10**

-0.28***

0.41**

-0.12**

 RS-Chest Symptoms

0.50**

-0.17**

0.40**

-0.10**

-0.28***

0.44**

-0.15***

  1. †Spearman's rank-order correlation; E-RS mean weekly scores (Day -7 to Day -1).
  2. ‡Clinic visit, Day 1, prior to treatment.
  3. Bold coefficients identify constructs with strongest expected relationship.
  4. *p < 0.05; **p < 0.01; ***p < 0.001.
  5. Abbreviations: 6MWT 6-minute walk test, AZ AstraZeneca, E-RS Exacerbations of Chronic Pulmonary Disease Tool - Respiratory Symptoms, FPI-SF Functional Performance Inventory - Short Form, ISWT Incremental Shuttle Walk Test, SGRQ St. George's Respiratory Questionnaire, SGRQ-C St. George's Respiratory Questionnaire for COPD.
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Respiratory Research

ISSN: 1465-993X

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