Figure 1

E-RS Scores by Level of Dyspnoea and Rescue Medication Use. A: Level of Dyspnea (mMRC^†). ^†Mpex data only; E-RS mean weekly scores (Day -7 to Day -1); ANCOVA controlling for age, co-morbidity, and baseline FEV₁. ***p < 0.001; ****p < 0.0001 from global test of differences between levels. Abbreviations: ANCOVA = analysis of covariance; E-RS = Exacerbations of Chronic Pulmonary Disease Tool - Respiratory Symptoms; FEV₁ = forced expiratory volume in 1 second; mMRC = modified Medical Research Council dyspnoea scale. B: Rescue Medication Use^†. ^†Results for AZ 1 data shown; similar results were found in AZ 2 data; E-RS and rescue medication use are mean weekly values (Day -7 to Day -1); Students t-test. ****p < 0.0001. Abbreviations: AZ = AstraZeneca; E-RS = Exacerbations of Chronic Pulmonary Disease Tool - Respiratory Symptoms.