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Table 6 Association of change in expression of neutrophil activation markers and susceptibility with change in number of bronchial NP57 + neutrophils in bronchial biopsies

From: Increased activation of blood neutrophils after cigarette smoking in young individuals susceptible to COPD

Outcome variable: change in number of bronchial NP57+neutrophils with smoking

n = 39, R2β= 0.620

-

p-value

Change in CD54 expression (Tafter-Tbefore)

0.271

0.044*

NP57 expression at baseline

-0.597

<0.001*

Susceptibility, n/y

0.386

0.013*

Current smoking, n/y

0.309

0.037*

  1. Multiple regression model with susceptibility to COPD (y/n) as predictor value and change in expression of neutrophil count in bronchial biopsies after smoking (Tafter-Tbefore) as dependent variable. B = standardized regression coefficient. *Significant (p < 0.05).