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Table 2 Airway and systemic inflammation in colonised* and non-colonised samples

From: Inflammatory thresholds and the species-specific effects of colonising bacteria in stable chronic obstructive pulmonary disease

  Non-colonised samples Colonised samples p-value
  n = 119 n = 64
Median (IQR) CXCL8 (ng.ml -1 ) 83 (24-182) 162 (71-309) <0.001
Median (IQR) IL-1β (ng.ml -1 ) 0.6 (0.2-1.9) 1.4 (0.7-5.9) <0.001
Median (IQR) MPO (μg.ml -1 ) 17.1 (7.6-30.6) 29.5 (16.2-40.9) <0.001
Median (IQR) CRP (mg.l -1 ) 2.0 (1.0-8.0) 2.0 (1.0-5.0) 0.261
Median (IQR) Fibrinogen (g.l -1 ) 3.5 (3.2-4.1) 3.8 (3.3-4.4) 0.049
  1. *Bronchial colonisation defined as sputum sample positive Haemophilus influenzae (HI), Streptococcus pneumoniae (SP) and/or Moraxella catarrhalis (MC) using quantitative polymerase chain reaction (qPCR).