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Table 1 Clinical characteristics of stable COPD patients, and by colonisation status* at study onset

From: Inflammatory thresholds and the species-specific effects of colonising bacteria in stable chronic obstructive pulmonary disease

  Overall Non-colonised Colonised p-value
  n = 99 n = 64 n = 35  
  Mean (SD) Mean (SD) Mean (SD)  
Age (years) 72.1 (8.9) 72.0 (9.3) 72.0 (9.3) 0.947
FEV 1 (L) 1.32 (0.54) 1.36 (0.59) 1.24 (0.44) 0.318
FEV 1 (% predicted) 51.5 (21.6) 53.3 (21.7) 48.1 (21.4) 0.257
FVC (L) 2.80 (0.86) 2.84 (0.93) 2.74 (0.73) 0.607
FEV 1 / FVC ratio (%) 47.2 (13.0) 48.0 (13.4) 45.9 (12.3) 0.440
BMI (kg/m 2 ) 26.6 (5.8) 26.9 (5.8) 26.2 (5.8) 0.591
  Median (IQR) Median (IQR) Median (IQR)  
Exacerbation frequency 2.00 (1.00-3.00) 1.97 (1.04-3.03) 2.04 (1.00-2.89) 0.511
Smoking pack years 48.4 (24.4-67.5) 47.2 (25.4-64.7) 51.0 (25.4-105.6) 0.213
ICS dose (beclomethasone equivalent μg) 1000 (500-2000) 1000 (500-2000) 1000 (500-2000) 0.224
  N (%) N (%) N (%)  
Male gender 66 (67) 40 (63) 26 (74) 0.234
Current Smokers 34 (34) 23 (36) 11 (31) 0.651
Chronic Bronchitis 78 (79) 49 (77) 29 (83) 0.464
  1. *Bronchial colonisation defined as sputum positive for Haemophilus influenzae (HI), Streptococcus pneumoniae (SP) and/or Moraxella catarrhalis (MC) using quantitative polymerase chain reaction (qPCR).
  2. Definitions: ICS = inhaled corticosteroids; BMI = body mass index.
  3. p-value refers to unpaired t-test between non-colonised and colonised patients.