Local association plots for the top two loci in the meta-analysis of COPD subjects with chronic bronchitis versus COPD subjects without chronic bronchitis in COPDGene non-Hispanic whites, GenKOLS, and ECLIPSE. A. rs114931935 on 1q23. B. rs924777 on 1q23. The x-axis is chromosomal position, and the y-axis shows the –log10 P value. The most significant SNP at each gene is labeled in purple, with other SNPs colored by degree of linkage disequilibrium (r2). Plots were created using LocusZoom.