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Table 3 Morphometric analysis of lungs from mice administered CSF-1 during concurrent hyperoxia exposure

From: The effect of CSF-1 administration on lung maturation in a mouse model of neonatal hyperoxia exposure

   Normoxia Hyp + PBS Hyp + CSF-1
P5 % Tissue 34.92 ± 1.83 28.31 ± 1.83 32.15 ± 1.74
  % Airspace 65.08 ± 1.83 71.69 ± 1.83 67.85 ± 1.74
  MLI 113.00 ± 3.22 121.70 ± 7.97 116.40 ± 3.45
P35 % Tissue 36.97 ± 1.29 38.48 ± 2.01 36.92 ± 0.88
  % Airspace 63.03 ± 1.29 61.52 ± 2.01 63.08 ± 0.88
  MLI 64.99 ± 1.78 72.66 ± 1.22 a* 75.27 ± 2.79 b**
  1. Morphometric estimation of percentage tissue, percentage airspace and mean linear intercept at P5 at the cessation of treatment (n = 4-5/group), and at P35 (n = 6-7/group). Data were analysed by one-way ANOVA and Tukey’s post-hoc test. `a’ represents significant difference between Norm and Hyp + PBS, `b’ represents significant difference between Norm and Hyp + CSF-1. *p < 0.05, **p < 0.01.