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Table 1 The clinical findings of the 52 patients with acute exacerbation of idiopathic pulmonary fibrosis on admission

From: Autopsy analyses in acute exacerbation of idiopathic pulmonary fibrosis

Characteristic

Data

Patient, No. (male/female)

52 (38/14)

Age, years old, mean (range)

71.1 (47–86)

Smoking (current/former/never)

9/22/21

Symptoms

 

 Dyspnea

52 (100%)

 Cough

41 (78.8%)

 Fever

22 (42.3%)

 Hemoptysis

2 (3.8%)

Comorbidities

 

 Diabetes

18 (34.6%)

 Chronic heart failure

12 (23.1%)

 Cancer

7 (13.5%)

 Pulmonary hypertension

1 (1.9%)

Prior treatment(s)

 

 Corticosteroid monotherapy

13 (25.0%)

 Corticosteroid plus immunosuppressive agent

12 (23.1%)

 Pirfenidone

5 (9.6%)

 Home oxygen therapy

15 (28.8%)

Blood sample findings

 

 WBC, /μl, mean (range)

11434 (4000–21300)

 CRP, mg/dl, mean (range)

9.36 (0.1-25.9)

 LDH, IU/L, mean (range)

479.2 (138–4135)

 KL-6, U/ml, mean (range)

1855 (507–7280)

 SP-D, ng/ml, mean (range)

545 (144–2500)

  1. Data are presented as the n and means.