From: Autopsy analyses in acute exacerbation of idiopathic pulmonary fibrosis
Characteristic | Data |
---|---|
Patient, No. (male/female) | 52 (38/14) |
Age, years old, mean (range) | 71.1 (47–86) |
Smoking (current/former/never) | 9/22/21 |
Symptoms | Â |
 Dyspnea | 52 (100%) |
 Cough | 41 (78.8%) |
 Fever | 22 (42.3%) |
 Hemoptysis | 2 (3.8%) |
Comorbidities | Â |
 Diabetes | 18 (34.6%) |
 Chronic heart failure | 12 (23.1%) |
 Cancer | 7 (13.5%) |
 Pulmonary hypertension | 1 (1.9%) |
Prior treatment(s) | Â |
 Corticosteroid monotherapy | 13 (25.0%) |
 Corticosteroid plus immunosuppressive agent | 12 (23.1%) |
 Pirfenidone | 5 (9.6%) |
 Home oxygen therapy | 15 (28.8%) |
Blood sample findings | Â |
 WBC, /μl, mean (range) | 11434 (4000–21300) |
 CRP, mg/dl, mean (range) | 9.36 (0.1-25.9) |
 LDH, IU/L, mean (range) | 479.2 (138–4135) |
 KL-6, U/ml, mean (range) | 1855 (507–7280) |
 SP-D, ng/ml, mean (range) | 545 (144–2500) |