Figure 4From: MicroRNA-708 regulates CD38 expression through signaling pathways JNK MAP kinase and PTEN/AKT in human airway smooth muscle cellsEffect of miR-708 in combination with miR-140-3p on ADP-ribosyl cyclase activity in NA-HASM cells. Cells (n = 3 donors) were co-transfected with equimolar concentrations of miR-708 and miR-140-3p, miR-708 mimic alone or the corresponding control scrambled sequence mimic at the indicated concentrations followed by exposure to 10 ng/ml rh-TNF-α (T) and measurement of ADP-ribosyl cyclase activity. Data represents mean ± SEM. Note that no additive effect was observed in cells transfected with equimolar concentrations of miR-708 and miR-140-3p relative to miR-708 alone.Back to article page