Figure 3

PlGF activates JNK and PKCδ signaling pathways in LE cells. (A-C) AEC II and (D) BEAS-2B were treated with 100 ng/ml recombinant human mouse PlGF respectively for 0–24 h. Cellular lysates were subjected to Western blot analysis with antibodies for phosphorylated p38 MAPK (p-p38 MAPK) and p38 MAPK (A), phosphorylated JNK (p-JNK) and JNK (B), phosphorylated PKCδ (p-PKCδ) and PKCδ (C and D). Data are presented as mean ± SEM. ^*p < 0.05 vs. vehicle-treated group.