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Figure 2 | Respiratory Research

Figure 2

From: Nitric oxide exerts protective effects against bleomycin-induced pulmonary fibrosis in mice

Figure 2

The n/i/eNOS−/−mice showed a deterioration of lung fibrosis in a pulmonary fibrosis model at two weeks after BLM-treatment. (A) Hematoxylin-eosin staining in normal saline (NS)-treated mice. Scale bar = 100 μm. (B) Hematoxylin-eosin staining, Masson-trichrome staining, α-SMA staining, MAC-2 staining in BLM-treated mice. Scale bar = 100 μm. (C) The fibrotic tissue area (blue-stained). (D) The collagen content in lung tissue. White and black bars indicate NS- (n= 3) and BLM- (n = 5) treated mice, respectively. *P < 0.05 vs. BLM-treated WT mice.

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