From: Surfactant alteration and replacement in acute respiratory distress syndrome
 | Hallman et al. [23]a | Pison et al. [24]b | Gregory et al. [25]c | Günther et al. [26]b | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
 |  |  |  | Low- | High- |  |  |  |  |  | ARDS |  |
 |  |  |  | score | score |  |  |  |  |  | + |  |
PL | Normal | ARDS | Normal | ARDS | ARDS | Normal | At risk | ARDS | Normal | ARDS | PNEU | PNEU |
Total | 0.6 | 0.6 | 84.1 | 65.7 | 65.1 | 7.99 | 3.48 | 2.47 | 29.38 | 28.11 | 22.57 | 21.82 |
 | μM | μM | μg/ml | μg/ml | μg/ml | μmol/ml | μmol/ml | μmol/ml | μg/ml | μg/ml | μg/ml | μg/ml |
PC | 73 | 59.5 | 62.8 | 56.3 | 48.1 | 76.27 | 73.32 | 62.64*** | 83.1 | 81.9 | 76.8 | 79.2 |
PG | 12.4 | 0.3*** | 10.02 | 1.6 | 1.88 | 11.58 | 7.26 | 6.48*** | 8.6 | 3.5*** | 2.4*** | 5.2** |
PI | 2.7 | 3.1 | 8.32 | 13.54 | 13.95 | 3.88 | 4.71 | 6.94** | 3.2 | 6.5* | 8.0*** | 5.5* |
PE | 2.6 | 4.3 | 4.82 | 13.65 | 18.68 | 3.32 | 4.9 | 5.86* | 1.7 | 1.9 | 2.6 | 2.4 |
PS | 3.3 | 13.0*** | 4.5 | n.d. | n.d. | 1.8 | 3.75 | 2.84 | 1.2 | 1.8 | 1.7 | 2.4 |
Sph | 3.7 | 17.5*** | 7.37 | 12.28 | 14.21 | 1.45 | 1.56 | 5.45*** | 0.8 | 3.5** | 5.2*** | 4.3*** |
LPC | 0.4 | 1.5 | 1.3 | 1.7 | 1.0 | 0.16 | 1.34 | 2.32* | 0.1 | 0.3 | 0.2 | 0.2 |