Figure 2

Immunocytochemical identification of T cells (CD3), total eosinophils (major basic protein; MBP), activated eosinophils (EG2) and mast cells (tryptase) in airways less than 2 mm in diameter (top) and in airways greater than 2 mm in diameter (bottom) from patients with asthma. Results given are average data from six (<2 mm) or 10 (>2 mm) airways from four to six asthmatic patients and 13 (<2 mm) or 31 (>2 mm) airways from six to 10 control individuals. ^*P < 0.05, ^***P < 0.001 versus nonasthmatic, control individuals. Pi, internal perimeter. Adapted from Hamid et al. [4].