Figure 1
From: Acute oxygen sensing: diverse but convergent mechanisms in airway and arterial chemoreceptors
Schematic flow diagram illustrating the diverse but converging transduction pathways linking hypoxia to transmitter release from arterial (carotid body) and airway (neuroepithelial body) chemoreceptors. Kv3.3 channel, voltage-activated shaw K+ channel (KCNC3); Maxi K, high-conductance, Ca2+-activated K+ channel (KCMA1); ROS, reactive oxygen species; TASK, TWIK-related, acid-sensitive K2P channel; TWIK, tandem of P-domains, weakly inward rectifying K2P channel.