Matrix metalloproteinases in lung biology

Respiratory Research

Table 1 Matrix metalloproteinases (MMPs)

MMP designation^*	Common name (other or previous names)
MMP-1	Collagenase-1 (fibroblast collagenase, interstitial
	collagenase)
MMP-2	Gelatinase-A (72 kDa gelatinase, 72 kDa type IV
	collagenase)
MMP-3	Stromelysin-1 (transin-1)
MMP-7	Matrilysin (PUMP)
MMP-8	Collagenase-2 (neutrophil collagenase)
MMP-9	Gelatinase-B (92 kDa gelatinase, 92 kDa type IV
	collagenase)
MMP-10	Stromelysin-2 (transin-2)
MMP-11	Stromelysin-3
MMP-12	Macrophage metalloelastase
MMP-13	Collagenase-3 (rat collagenase)
MMP-14	MT1-MMP (membrane-type MMP)
MMP-15	MT2-MMP
MMP-16	MT3-MMP
MMP-17	MT4-MMP
MMP-18	Collagenase-4^†
MMP-19
MMP-20	Enamelysin
MMP-21
MMP-22
MMP-23	CA-MMP
MMP-24	MT5-MMP
MMP-25	Leukolysin (MT6-MMP)
MMP-26	Endometase (matrilysin-2)

^*There is no MMP-4, MMP-5, or MMP-6. After matrilysin was discovered and designated as MMP-7, MMP-4 to MMP-6 were determined to be either MMP-2 or MMP-3. ^†Collagenase-4 was isolated from Xenopus. A mammalian homolog has not been found.

ISSN: 1465-993X