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Table 1 Hypoxia-inducible gene expression

From: Oxygen-regulated transcription factors and their role in pulmonary disease

Gene product Transcription factor*
Adenylate kinase 3 HIF-1
α1B-Adrenergic receptor HIF-1
Adrenomedullin HIF-1
Aldolase A HIF-1
Aldolase C HIF-1
Carbonic anhydrase-9 HIF-1
Ceruloplasmin HIF-1
Cyclooxygenase-2 HMG I(Y), NF-κB
Endothelin-1 HIF-1
Enolase-1 HIF-1
Erythropoietin HIF-1
GADD153 Not determined
Glucose transporter-1 HIF-1
Glucose transporter-3 HIF-1
Glyceraldehyde-3-phosphate HIF-1
dehydrogenase  
Heme oxygenase-1 AP-1, HIF-1
Hexokinase-1 HIF-1
Hexokinase-2 HIF-1
Insulin-like growth factor-2 (IGF-2) HIF-1
IGF-binding protein-1 HIF-1
IGF-binding protein-2 HIF-1
IGF-binding protein-3 HIF-1
Interleukin-6 NF-IL6
Lactate dehydrogenase A HIF-1
Nitric oxide synthase-2 HIF-1
NIP3 HIF-1
Ornithine decarboxylase Not determined
p21 HIF-1
p27 Not determined
p35srj HIF-1
Phosphofructokinase L HIF-1
Phosphoglycerate kinase-1 HIF-1
Plasminogen activator inhibitor-1 HIF-1
Prolyl-4-hydroxylase α (I) HIF-1
Pyruvate kinase M HIF-1
Tissue factor EGR-1
Transferrin HIF-1
Transferrin receptor HIF-1
Transforming growth factor β3 HIF-1
Triosephosphate isomerase HIF-1
Tyrosine hydroxylase AP-1
Vascular endothelial growth factor (VEGF) HIF-1
VEGF receptor FLT-1 HIF-1
  1. *See [12] for literature citations.