Figure 3
From: Epithelial antimicrobial peptides in host defense against infection
Structure of prototypical genes and peptides of the defensin and cathelicidin families. Both gene types have several exons whose primary translational product is a prepropeptide. The C-terminus is the part of the molecules that contains antimicrobial activity. The genes are represented schematically with the following individual components: 5' untranslated region (5' UTR), white box; signal sequence, shaded box; prosequence, black box; mature peptide, hatched box; 3' UTR, white box.