Figure 2

Effect of dexamethasone (0.01 - 3 mg/kg) on peak changes in PenH measured after aerosolised methacholine (3 mg/ml for 60sec) 24 hours after the last antigen challenge in sensitised mice (Figure 2A). Effect of dexamethasone (1 mg/kg) on peak changes in PenH measured after aerosolised methacholine (3 - 100 mg/ml for 60sec) 24 hours after the last antigen challenge in sensitised mice (Figure 2B). Results represent mean ± s.e.m. (n = 10). * P < 0.05 compared with relevant vehicle dosed control group.