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Table 3 Genotype frequencies of TNF-α +489 G/A gene polymorphism in subgroups of COPD patients versus population control group*

From: Tumor Necrosis Factor-α +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease

 

GG

GA

AA

P-value †

Patients versus controls

Patients without radiological emphysema

18 (62)

11 (38)

0

0.004

Patients with radiological emphysema

92 (77)

26 (22)

1 (1)

0.131

Population controls

264 (84)

45 (14)

6 (2)

 
  1. * Values are expressed as absolute numbers; percentages are given in parentheses. For technical reasons, not all the samples were successfully genotyped. † χ2-test of the genotype frequencies of TNF-α +489G/A gene polymorphism. Statistical significance was defined as p < 0.025 using Bonferroni correction.
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Respiratory Research

ISSN: 1465-993X

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