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Table 2 Clinical characteristics of subgroups of COPD patients without and with radiological emphysema *

From: Tumor Necrosis Factor-α +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease

 

Patients without radiological emphysema

Patients with radiological emphysema

 
 

(n = 32)

(n = 127)

P-value †

Age (year)

66 ± 8

66 ± 8

0.70

Sex (male/female)

16/16

86/41

0.062

FEV1% predicted

46 ± 15

35 ± 11

0.001

Smoking behavior

   

   -never smoked/(ex)-smoker

4/28

1/126

0.001

   -pack years

26 ± 22

34 ± 18

0.037

  1. * Values are expressed as mean ± SD or as absolute numbers. † The Mann-Whitney U test was used for differences in age and FEV1 between groups. The χ2-test was used to detect significant differences in genotype frequencies and sex. Statistical significance was defined as p < 0.01 using Bonferroni correction.