Table 1 Genotype frequencies of TNF-α -376G/A, -308G/A, -238G/A and +489G/A gene polymorphisms in COPD patients and population control group*
Genotype | COPD | Control | P-value † |
|---|---|---|---|
TNF -376G/A | |||
GG | 162 (98) | 306 (99) | |
GA | 3 (2) | 3 (1) | 0.562 |
AA | 0 (0) | 1 (0) | |
TNF -308G/A | |||
GG | 113 (69) | 237 (71) | |
GA | 49 (30) | 91 (27) | 0.397 |
AA | 1 (1) | 7 (2) | |
TNF -238G/A | |||
GG | 151 (92) | 310 (94) | |
GA | 13 (8) | 20 (6) | 0.544 |
AA | 0 (0) | 1 (0) | |
TNF +489G/A | |||
GG | 118 (75) | 264 (84) | |
GA | 38 (24) | 45 (14) | 0.019 |
AA | 1 (1) | 6 (2) |