Table 2 The array of proteins encoded by genes directly controlled by NF-κB
Protein type | Protein |
|---|---|
Cytokines/growth factors | IL-1α |
|  | IL-1β |
| Â | IL-2 |
| Â | IL-3 |
| Â | IL-6 |
| Â | IL-8 |
| Â | IL-12 |
|  | TNF-α |
|  | Lymphotoxin-α |
|  | Interferon-β |
| Â | Granulocyte Colony-Stimulating |
| Â | Factor |
| Â | Macrophage Colony-Stimulating |
| Â | Factor |
| Â | Granulocyte-Macrophage Colony- |
| Â | Stimulating Factor |
Cytokine receptors | IL-2 receptor α chain |
Stress proteins | Serum amyloid A protein |
| Â | Complement factors B, C3 and C4 |
|  | α1-acid glycoprotein |
Adhesion molecules | Intracellular adhesion molecule-1 |
| Â | Vascular cell adhesion molecule-1 |
| Â | Mucosal addressin cell adhesion molecule-1 |
| Â | E-selectin |
Immunoregulatory molecules | Immunoglobulin κ light chain |
| Â | MHC class I and II |
|  | T-cell receptor α and β |
|  | β2-Microglobulin |
| Â | Invariant chain |
| Â | Transporter associated with antigen processing |
| Â | Proteasome subunit |
| Â | Inducible nitric oxide synthase |
|  | Inhibitory κB |
| Â | p53 |