SLPI and multiorgan failure score (MOFS) in patients with acute lung injury. The extent of organ involvement and severity of organ failure were quantified with a modified Goris organ failure score. SLPI levels were measured by enzyme-linked immunosorbent assay in bronchoalveolar lavage from 35 patients with acute lung injury. SLPI levels were correlated with MOFS (r = 0.55; P = 0.0028). This suggests that SLPI could be used as a marker for acute lung injury. Indeed, we found recently that SLPI is increased in patients at risk of developing ARDS who later developed the disease, compared with patients at risk of ARDS who did not develop the disease .